Plastic is a recurrent element in our daily lives. Only about 15% of total plastic consumed is recycled, while the rest is often dumped into the environment. The Amazon is not an exception. In some areas, the banks of the Amazon River look like this picture. Plastics are dangerous for large mammals, like freshwater dolphins and manatees, fish and birds. Moreover, they breakdown into smaller particles, the so-called microplastics, that can be ingested by smaller animals such as freshwater invertebrates. The SILENT AMAZON project will assess for the first time the presence and spread of plastics and microplastics in the wide Amazon, and will comparatively assess the plastic pollution status of this river with other large rivers in the world.